Superdrol is an anabolic androgenic steroid. The active compound is metasterone (IUPAC system name: 17β-Hydroxy-2α, 17α-dimethyl-5α-androstan-3-one), also known as methyldrostanolone and metasterone.
Methylhydroxynandrolone was first described in 1964 following experiments on the hydroxylation of nandrolone. Due to the 4-hydroxy group, this derivative is not affected by 5-alpha-reductase. Although it showed good results, it did not find its way to medical use. Only its unmethylated cousin, oxabolone, has reached the drug stage. For 40 years this steroid was forgotten. In 2004, it suddenly appeared on the American market as a dietary supplement. It was sold without restriction as it was not subject to the 1991 law and was still on the list of anabolics as of January 20, 2005. This marked the end of the commercial era of this drug.
Properties of the drug
Methylhydroxynandrolone is a powerful derivative of nandrolone. It is an orally active drug, does not aromatize and is an anabolic steroid with no estrogenic activity. According to early research, methylhydroxynandrolone is 13 times more anabolic and 3 times more androgenic than methyltestosterone. It resembles trenbolone more than nandrolone in its androgenic effects. Its 4-hydroxy group prevents it from being converted into active metabolites in the skin and prostate.
Methylhydroxynandrolone is a modified form of nandrolone. It differs by: 1) adding a methyl group at the 17-alpha position to protect the hormone when taken orally, and 2) adding a hydroxyl group at the 4-position, which prevents aromatization, progestagenic activity, 5 – a conversion and reduced relative androgenicity.
Estrogen Side Effects
Methylhydroxynandrolone does not aromatize and has no estrogenic activity. Anti-estrogens are not necessary, sensitive people will not experience symptoms of gynecomastia. Estrogen normally causes water retention, but with this steroid you will build quality mass without excess fluid. This makes it ideal for cutting applications where water and grease retention is the primary concern.
Androgenic side effects
Methylhydroxynandrolone is classified as anabolic, but androgenic side effects are still possible. Oily skin, acne, hair growth on the body and face can be increased. High doses are likely to cause them. Anabolic steroids can make hair loss worse in men. Women should also be aware of the potential virilizing effects of AAS. This can include a deeper voice, irregular periods, changes in skin texture, facial hair, and clitoral enlargement. Methylhydroxynandrolone does not react with 5a-reductase and its androgenicity cannot be altered by co-administration with finasteride or dutasteride.
Androgenic side effects
Methylhydroxynandrolone is a c17 alpha alkylated drug. This change protects the drug from liver deactivation, allowing a greater percentage of the drug to enter the bloodstream after oral ingestion. Alkylated AAS can be hepatotoxic. Long-term use or high doses may cause liver damage. In rare cases, life-threatening malfunctions may develop. It is advisable to periodically consult a doctor during the course to monitor liver function. The consumption of alkylated AAS is generally limited to 6-8 weeks to avoid additional stress on the liver. The use of liver cleansing supplements such as Liver Stabil, Liv-52 and Essentiale Forte may be recommended during the course.
The cardiovascular system
AAS can negatively affect blood cholesterol levels. This may be a drop in the “good” HDL level, a shift in the balance towards the risk of arteriosclerosis. The relative effect of AAS on lipids depends on dose, route of administration, type of steroid, and degree of resistance to hepatic metabolism.
Methylhydroxynandrolone has a potent effect on hepatic cholesterol regulation due to its non-aromatizing structure, structural resistance to degradation, and route of administration. AAS can negatively affect blood pressure and triglycerides, decrease vascular endothelial relaxation, cause ventricular enlargement of the heart, and potentially increase the risk of cardiovascular disease and heart attack. In order to reduce the load on the cardiovascular system, it is recommended to minimize the intake of saturated fats, cholesterol and simple carbohydrates during AAS. The use of food supplements such as fish oil, lipid stabilizers or similar products is recommended.
Suppression of testosterone
All AAS in doses required for muscle building suppress the body’s production of testosterone. Without the intervention of testosterone-boosting substances, testosterone returns to normal levels within 1-4 months after the cycle. Be aware that hypogonadotropic hypogonadism can become secondary in the long term and this may require medical intervention.
The side effects listed above are not all the side effects they may have. For a detailed study, read the Side Effects chapter of this book.
Studies have shown that taking AAS by mouth with food decreases the drug’s bioavailability. This is due to the fat-soluble nature of AAS, which may cause some of the drug to dissolve in fat from the diet, thereby reducing the absorption of AAS from the gastrointestinal tract. For maximum effect, this medication should be taken on an empty stomach.
Reception for men
Methylhydroxynandrolone is not approved for human use. An effective dose for improving physical condition is 2-10 mg. In order to minimize the load on the liver, it is necessary to limit the intake to 6-8 weeks. At this dose, methylhydroxynandrolone allows a very good increase in dry matter without water retention or fat growth. Methylhydroxynandrolone is not considered a bulking drug and is stacked with other steroids depending on the user’s individual goals.
Reception for women
Methylhydroxynandrolone is not approved for human use. The high ratio of anabolic to androgenic effect allows it to be used in doses of 1-3 mg per day without any signs of virilization.